Science - an area of human activity, aimed at the elaboration and systematization of objective knowledge of reality. The basis of this activity is to collect the facts, their constant updating and systematization, critical analysis and, on that basis, the synthesis of new knowledge or generalizations that not only describe the observed natural or social phenomena, but also allow us to construct a cause-effect relationship with the ultimate goal of forecasting.

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Polydeoxyribonucleotides enhance the proliferation of human skin fibroblasts: Involvement of A2 purinergic receptor subtypes

Life Sciences, Volume 64, Issue 18, 26 March 1999, Pages 1661-1674

Stefano Thellung, Tullio Florio, Alberto Maragliano, Giulia Cattarini, Gennaro Schettini

Polydeoxyribonucleotide (PDRN) restores blood flow in an experimental model of peripheral artery occlusive disease

Alessandra Bitto, MDa, Francesca Polito, PhDa, Domenica Altavilla, PhDa, Letteria Minutoli, MDa, Alba Migliorato, PhDb, Francesco Squadrito, MDa

Activation of adenosine A2A receptors by polydeoxyribonucleotide increases vascular endothelial growth factor and protects against testicular damage induced by experimental varicocele in rats

Fertility and Sterility, Volume 95, Issue 4, 15 March 2011, Pages 1510-1513

Letteria Minutoli, Salvatore Arena, Giulio Bonvissuto, Alessandra Bitto, Francesca Polito, Natasha Irrera, Francesco Arena, Eugenia Fragalà, Carmelo Romeo, Piero Antonio Nicotina, Carmine Fazzari, Herbert Marini, Alessandra Implatini, Silvia Grimaldi, Noemi Cantone, Vincenzo Di Benedetto, Francesco Squadrito, Domenica Altavilla, Giuseppe Morgia

Characterization and quantitation of the active polynucleotide fraction (PDRN) from human placenta, a tissue repair stimulating agent Original Research Article

Journal of Pharmaceutical and Biomedical Analysis, Volume 14, Issue 11, August 1996, Pages 1555-1560

Giuseppe Tonello, Marcello Daglio, Nadia Zaccarelli, Enzo Sottofattori, Mauro Mazzei, Alessandro Balbi

Effects of polydeoxyribonucleotides (PDRN) on wound healing: Electric cell-substrate impedance sensing (ECIS)Original Research Article

Materials Science and Engineering: C, Volume 69, 1 December 2016, Pages 554-560

Youngmi Koo, Yeoheung Yun

Subdermal minimal surgery with hyaluronic acid as an effective treatment for neck wrinkles

Journal of the American Academy of Dermatology, Volume 66, Issue 4, Supplement 1, April 2012, Page AB208

Study of the effect of mixing approach on cross-linking efficiency of hyaluronic acid-based hydrogel cross-linked with 1,4-butanediol diglycidyl etherOriginal Research Article

European Journal of Pharmaceutical Sciences, Volume 91, 25 August 2016, Pages 131-137

Complications of hyaluronic acid fillers and their managements Review Article

Journal of Dermatology & Dermatologic Surgery, Volume 20, Issue 2, July 2016, Pages 100-106

Mohammed H. Abduljabbar, Mohammad A. Basendwh

Key importance of compression properties in the biophysical characteristics of hyaluronic acid soft-tissue fillers Original Research Article

Journal of the Mechanical Behavior of Biomedical Materials, Volume 61, August 2016, Pages 290-298

Samuel Gavard Molliard, Séverine Albert, Karine Mondon

Hyaluronic Acid Fillers: Science and Clinical Uses Review Article

Clinics in Plastic Surgery, Volume 43, Issue 3, July 2016, Pages 489-496

Karol A. Gutowski

Intralesional Injection of Hyaluronic Acid in Patients Affected With Peyronie's Disease: Preliminary Results From a Prospective, Multicenter, Pilot Study Original Research Article

Sexual Medicine, Volume 4, Issue 2, June 2016, Pages e85-e90

Alessandro Zucchi, Elisabetta Costantini, Tommaso Cai, Giorgio Cavallini, Giovanni Liguori, Vincenzo Favilla, Gaetano De Grande, Giuseppe D'Achille, Mauro Silvani, Giorgio Franco, Alessandro Palmieri, Paolo Verze, Vincenzo Mirone

A comparison of a refrigerant and a topical anesthetic gel as preinjection anesthetics: A clinical evaluation Original Research Article

The Journal of the American Dental Association, Volume 140, Issue 1, January 2009, Pages 68-72

Amar Kosaraju, Kraig S. Vandewalle

Chapter 10 - Local Anesthetics

Side Effects of Drugs Annual, Volume 38, 2016, Pages 97-104

Sujana Dontukurthy, Allison Kalstein, Joel Yarmush

Ex-situ catalytic pyrolysis of citrus fruit peels over mesoporous MFI and Al-MCM-41Original Research Article

Energy Conversion and Management, Volume 125, 1 October 2016, Pages 277-289

Young-Min Kim, Jungho Jae, Hyung Won Lee, Tae Uk Han, Heejin Lee, Sung Hoon Park, Seungdo Kim, Chuichi Watanabe, Young-Kwon Park

Quality characteristics of beef sausage containing pomegranate peels during refrigerated storage Original Research Article

Annals of Agricultural Sciences, Volume 60, Issue 2, December 2015, Pages 403-412

Mesotherapy, Microneedling, and Chemical Peels Review Article

Clinics in Plastic Surgery, Volume 43, Issue 3, July 2016, Pages 583-595

Johnson C. Lee, Mark A. Daniels, Malcolm Z. Roth